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PROGRAMMA
09.00 - 09.15 Presentazione dell'SZN e saluti del Presidente Roberto Danovaro, saluti del coordinatore dell’NBG Ennio Del GiudicePRIMA SESSIONE Chair: P. Sordino (SZN), G. Andria (UNINA)
09.15 - 9.30: Brain metabolic DNA is synthesized by reverse trascription in cytoplasmic organelles (Rutigliano, UNINA)
09.30 - 9.45: Regulation of trafficking and folding of cellular prion protein PrPC and its shadow Shadoo (Sarnataro, UNINA/CEINGE)
09.45 - 10.00: Characterization of smn-1 genetic interactors in a C.elegans SMA model (Santonicola, IBBR)
10.00 - 10.15: Study of neural stem cell biology in a mouse model of Rett syndrome (Squillaro, UNINA2)
10.15 - 10.30: Nerve regeneration in the cephalopod mollusc Octopus vulgaris: from images to discoveries (Imperadore, SZN)
10.30 - 10.45: Orexin and endocannabinoid morphological interactions in the brain of adult zebrafish (Imperatore, UNISANNIO/ICB)
10.45 - 11.00: Shutting down ranslation of Amyloid Precursor protein in early symptomatic hAPP mutan mice rescues the Alzheimer Disease phenotype (Borreca, IBCN)
11.00 - 11.30 COFFEE BREAK e POSTERS
SECONDA SESSIONE Chair: M. Cataldi (UNINA), G. Fiorito (SZN)
11.30 - 11.45: Protocadherins and their role in brain complexity – a tale from Octopus (Styfhals, SZN)
11.45 - 12.00: Evidence of increased oxidative stress in Pompe disease. A new therapeutic target? (Tarallo, UNINA/TIGEM)
12.00 - 12.15: Inhibition of monoacylglycerol lipase terminates diazepamresistant status epilepticus in mice and its effects are potentiated by a ketogenic diet (Terrone, UNINA/M.Negri)
12.15 - 12.30: Orexin-Aenhances dopaminergic signaling in the brain of obese mice (Tunisi, ICB/UNINA)
12.30 - 12.45: Onecut gene function in the CNS of chordates: development and evolution (Locascio, SZN)
12.45 - 13.00: Targeting neuronal proteostasis to treat the CNS in lysosomal storage diseases (Monaco, TIGEM)
13.00 - 14.00 LUNCH BREAK e SESSIONE POSTERS
TERZA SESSIONE Chair: E. Di Schiavi (IBBR), B. Franco (TIGEM)
14.00 - 14.15: Myoclonic Epilepsy of Unverricht and Lundborg (EPM1): understanding the role of Cystatin b in human cerebral organoids (Pipicelli, UNINA/Max Planck)
14.15 - 14.30: A rat model of perinatal stress: impact on gene expreession of glutamatergic postsynaptic density genes (Avagliano, UNINA)
14.30 - 14.45: Modulation of aging pathways as a therapeutic strategy for Parkinson’s disease (Decressac, TIGEM)
14.45 - 15.00: Alteration of endosomal trafficking is associated with neurodegenerative diseases (Paladino, UNINA/CEINGE)
15.00 - 15.15: Effects of Methylcyclopentadienyl Manganese Trycarbonil on dopaminergic neurons in zebrafish (Fasano, SZN/UNISANNIO)
15.15 - 15.30: Striatonigral involvement in Fabry Disease: a quantitative and volumetric MRI study (Russo, UNINA)
15.30 - 16.00 COFFEE BREAK e SESSIONE POSTERS
QUARTA SESSIONE Chair: C. Lucini (UNINA), M. Taglialatela (UNINA)
16.00 - 16.15: The inflammatory response following acute seizures in zebrafish brain and in chordate evolution (Nittoli, SZN)
16.15 - 16.30: Pragmatic abilities in multiple sclerosis: an RS-FMRI study (Cocozza, UNINA)
16.30 - 16.45: Default Mode Network modifications in Fabry Disease (Cocozza, UNINA)
16.45 - 17.00: Brain functional changes and cognitive dysfunction in Friedreich's Ataxia (Cocozza, UNINA)
17.00 - 17.15: Dissecting PRUNE-1/NME1 function in brain and cerebellum of Microcephaly and Peho syndrome affected patients (Zollo, UNINA/CEINGE)
17.15 - 17.30: De novo gain-of-function variants in the Slo2 family of Na+activated K+ channels are responsible for developmental and epileptic encephalopathies (Manocchio, UNIMOL)
17.30 CLOSING REMARKS E. Del Giudice
